Optic Nerve Hypoplasia With Isolated Tortuosity of the Retinal Veins

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Optic nerve hypoplasia with isolated tortuosity of the retinal veins: a marker of endocrinopathy.

OBJECTIVE To investigate whether children with optic nerve hypoplasia and pituitary hormone insufficiencies have specific ocular fundus characteristics that may facilitate early diagnosis and treatment. DESIGN From May 15, 1995, through December 15, 1997, 17 children (8 girls and 9 boys, aged 0.3 to 13 years) with optic nerve hypoplasia were referred to the Department of Pediatric Ophthalmolo...

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Defining optic nerve tortuosity.

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Peripheral retinal nonperfusion associated with optic nerve hypoplasia and lissencephaly.

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Retinal Structure and Function in Eyes with Optic Nerve Hypoplasia

We investigated retinal structure and function in eyes with optic nerve hypoplasia (ONH). Twenty-nine eyes of 18 patients with ONH and 21 eyes of 21 control patients were analyzed. Spectral-domain optical coherence tomography (SD-OCT), full-field electroretinography (FF-ERG), and focal macular ERG (FM-ERG) were performed. SD-OCT analysis of the macular region showed significant ganglion cells c...

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Hypoplasia of the optic nerve.

Hypoplasia of the optic nerve is uncommon (Scheie and Adler, I94I; Somerville, I962; Whinery and Blodi, I963; Ewald, I967). It is usually due to a failure of development of the ganglion cell layer of the retina and results in a small but discernible optic disc with central vessels. The disc may be cupped with a peripapillary, mottled, yellowish halo corresponding to the size of the normal disc,...

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ژورنال

عنوان ژورنال: Archives of Ophthalmology

سال: 1999

ISSN: 0003-9950

DOI: 10.1001/archopht.117.7.880